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Applied Sciences, Vol. 16, Pages 9077: Conditional Deep Convolutional GAN for the Design of High-Performance Periodic Absorber Metasurfaces
1+ day, 8+ hour ago (271+ words) This work presents a conditional deep convolutional generative adversarial network (CDCGAN) for the inverse design of high-absorptance periodic metasurfaces (MSs) with different geometries. The conditioning mechanism encodes geometric and spectral parameters. A key innovation is the inclusion of unit cells…...
Applied Sciences, Vol. 16, Pages 9054: Chemical Composition, Cytotoxic and Antimicrobial Activities of Essential Oils from Two Croatian Lavandin ‘Budrovka’ Accessions (Lavandula × intermedia Emeric ex Loisel.)
2+ day, 6+ hour ago (546+ words) Lavandula × intermedia (lavandin) is among the most cultivated Lavandula species, valued for its high essential oil yield and broad applications across different industries. Although it has traditionally been regarded as inferior to true lavender (Lavandula angustifolia), particularly within the field…...
Applied Sciences, Vol. 16, Pages 8989: Genetic-Algorithm Optimization of Dynamic Efficiency in Bidirectional Porous Functionally Graded Beams
4+ day, 1+ hour ago (389+ words) This study develops an analytical–evolutionary framework for optimizing the dynamic efficiency of bidirectional porous functionally graded beams. Touratier’s higher-order shear deformation theory is coupled with a real-coded genetic algorithm. The material-gradation indices in the thickness and width directions, the…...
Applied Sciences, Vol. 16, Pages 8950: Pelargonium graveolens and Pelargonium zonale as Valuable Sources of Antioxidants to Be Applied in Cosmetic Preparations
5+ day, 45+ min ago (719+ words) Pelargonium graveolens and Pelargonium zonale are promising sources of natural antioxidants and other bioactive compounds that may find future use in topical cosmetic preparations. The aim of our study was to investigate the antioxidant properties and chemical composition of extracts…...
Applied Sciences, Vol. 16, Pages 8947: Targeting the Selectivity Barrier in One-Carbon Metabolism: Rutaecarpine Preferentially Inhibits MTHFD2 over MTHFD1
5+ day, 45+ min ago (436+ words) Folate-mediated one-carbon metabolism supports nucleotide biosynthesis, methylation reactions, and redox homeostasis, and the mitochondrial enzyme MTHFD2 has emerged as a cancer-associated metabolic target. However, the development of MTHFD2-preferential inhibitors remains challenging because MTHFD2 is structurally and functionally related to other folate-metabolism enzymes,…...
Applied Sciences, Vol. 16, Pages 8942: Development and Application of Computational Chemistry Methods
5+ day, 5+ hour ago (14+ words) Computational chemistry has become an essential bridge between microscopic theory and measurable chemical behaviour [...]...
Applied Sciences, Vol. 16, Pages 8932: Combinatorial Optimization of Promoters and Anchoring Proteins Drives a 10-Fold Enhancement in Yeast Surface Display of eGFP
5+ day, 21+ hour ago (423+ words) Yeast surface display (YSD) is a powerful tool for protein engineering, yet its broader application is often limited by suboptimal display efficiency. To address this, we systematically investigated the combinatorial effects of three key genetic determinants—promoter strength, anchoring protein…...
Applied Sciences, Vol. 16, Pages 8916: Suppressing Finite-Difference Dispersion in Wavefield Modeling via Simulated Annealing Optimization
6+ day, 2+ hour ago (271+ words) Numerical dispersion limits the accuracy of finite-difference elastic-wave modeling, particularly when relatively short spatial stencils are used. This study evaluates staggered-grid spatial-derivative coefficients obtained using a constrained simulated-annealing procedure and compares their spectral and numerical behavior primarily with Taylor-expansion coefficients…...
Applied Sciences, Vol. 16, Pages 8901: Leukocyte Differentiation and Scattergram Abnormalities in Rabbits Using the Mindray BC-60R Hematology Analyzer
6+ day, 5+ hour ago (472+ words) This study evaluated the performance of the Mindray BC-60R differential WBC count (AD) in comparison with a manual method (MD) in rabbits. Diagnostic blood samples were analyzed within 1 h of collection, and MD was performed by counting 100 leukocytes. Method comparison was…...
Applied Sciences, Vol. 16, Pages 8903: Concept-Bottleneck Models with Expert-Discovered Versus Automatically-Discovered Concepts: A Comparative Study on Fine-Grained Fungal Classification
6+ day, 5+ hour ago (385+ words) Interpretable-by-design architectures, such as Concept-Bottleneck Models (CBMs), are essential for trustworthy AI under regulations like the EU AI Act. While classical CBMs rely on costly expert labels, recent automated methods use vision–language models for concept discovery. However, whether automation…...